{"product_id":"glutathione-1500mg","title":"Glutathione 1500mg – Antioxidant Research Compound | Tides Lab","description":"\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eGlutathione (GSH) is an endogenous tripeptide (γ-L-glutamyl-L-cysteinyl-glycine) and the most abundant intracellular antioxidant in mammalian cells. It plays a central role in cellular redox homeostasis, xenobiotic detoxification, and immune regulation, and is one of the most widely studied compounds in biochemistry and oxidative stress research.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eThis 1500mg lyophilised formulation is supplied at ≥99% purity and intended strictly for laboratory research purposes.\u003c\/p\u003e\n\u003ch2 class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eKey Features\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul class=\"[li_\u0026amp;]:mb-0 [li_\u0026amp;]:mt-1 [li_\u0026amp;]:gap-1 [\u0026amp;:not(:last-child)_ul]:pb-1 [\u0026amp;:not(:last-child)_ol]:pb-1 list-disc flex flex-col gap-1 pl-8 mb-3\"\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003e1500mg lyophilised Glutathione (GSH)\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eEndogenous tripeptide studied in cellular redox and antioxidant research\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eInvestigated across oxidative stress, detoxification and immune signalling models\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003e≥99% purity\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eResearch use only\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eFast Australian shipping\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eMechanism Overview\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eGlutathione functions as the primary intracellular reducing agent, maintained predominantly in its reduced (GSH) form by glutathione reductase using NADPH as a cofactor. In laboratory research models, GSH exerts its antioxidant activity through direct scavenging of reactive oxygen species (ROS) and reactive nitrogen species (RNS), as well as through serving as an essential cofactor for glutathione peroxidase (GPx) enzymes, which catalyse the reduction of hydrogen peroxide and lipid hydroperoxides to non-toxic products.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eThe ratio of reduced GSH to oxidised glutathione (GSSG) is widely used in research as a reliable indicator of intracellular oxidative stress, making Glutathione a key reference compound in studies examining cellular redox state across a broad range of experimental models.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eBeyond its antioxidant role, Glutathione is central to Phase II hepatic detoxification research, where it acts as a conjugate for electrophilic xenobiotics and reactive metabolites via glutathione S-transferase (GST) enzymes, facilitating their excretion. This detoxification mechanism has made GSH a critical compound in hepatocyte and toxicology research models.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eGlutathione also plays a role in immune cell function, with research describing its involvement in T-cell proliferation, NK cell cytotoxicity, and the regulation of pro-inflammatory cytokine signalling. Antigen-presenting cells in particular require adequate intracellular GSH levels for effective antigen processing in experimental immune models.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eIts involvement across such a broad range of fundamental cellular processes makes Glutathione one of the most versatile and frequently referenced compounds in biochemical and pharmacological research.\u003c\/p\u003e\n\u003ch2 class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eStability and Handling\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eGlutathione is supplied in lyophilised (freeze-dried) form to preserve stability during storage and transport. As a thiol-containing compound, GSH is particularly susceptible to oxidation upon exposure to air, light, and elevated temperatures.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eStandard laboratory handling considerations include:\u003c\/p\u003e\n\u003cul class=\"[li_\u0026amp;]:mb-0 [li_\u0026amp;]:mt-1 [li_\u0026amp;]:gap-1 [\u0026amp;:not(:last-child)_ul]:pb-1 [\u0026amp;:not(:last-child)_ol]:pb-1 list-disc flex flex-col gap-1 pl-8 mb-3\"\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eRefrigerated or frozen storage following reconstitution\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eProtection from direct light and air exposure\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eUse of inert atmosphere conditions where possible during handling\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eAvoiding repeated temperature fluctuations\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eResearch Use Only\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eGlutathione is supplied strictly for laboratory research and educational purposes. It is not approved for therapeutic use and is not intended for human consumption.\u003c\/p\u003e\n\u003cp\u003e\u003cscribe-shadow id=\"crxjs-ext\" data-crx=\"okfkdaglfjjjfefdcppliegebpoegaii\" style=\"position: fixed; width: 0px; height: 0px; top: 0px; left: 0px; z-index: 2147483647; overflow: visible; visibility: visible;\"\u003e\u003c\/scribe-shadow\u003e\u003c\/p\u003e","brand":"Tides Lab Australia","offers":[{"title":"Default Title","offer_id":53334055256378,"sku":null,"price":159.0,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0987\/3892\/9978\/files\/Glutathione-1500mgweb.jpg?v=1777534496","url":"https:\/\/tideslabaustralia.com.au\/products\/glutathione-1500mg","provider":"Tides Lab Australia","version":"1.0","type":"link"}