Epithalon 50mg – Telomere & Longevity Research Peptide | Tides Lab

Epithalon (also referred to as Epitalon or Epithalamin) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from Epithalamin, a natural polypeptide produced by the pineal gland. It has been the subject of extensive research in the fields of ageing biology, telomere regulation, and neuroendocrine signalling, particularly within Russian scientific literature spanning several decades.

This 50mg lyophilised formulation is supplied at ≥99% purity and intended strictly for laboratory research purposes.

Key Features

• 50mg lyophilised Epithalon
• Synthetic tetrapeptide studied in telomere biology and ageing research
• Investigated in pineal gland, neuroendocrine and cell cycle regulation models
• ≥99% purity
• Research use only
• Fast Australian shipping

Mechanism Overview

Epithalon is a tetrapeptide analogue of Epithalamin, an endogenous pineal extract associated with the regulation of melatonin synthesis and neuroendocrine homeostasis. Its primary area of research interest lies in its proposed interaction with telomerase — the enzyme responsible for maintaining telomere length during cell division.

In laboratory research models, Epithalon has been described as activating telomerase activity in somatic cells, which would otherwise exhibit declining telomere length with successive divisions. Telomere shortening is widely studied as a biomarker of cellular ageing and replicative senescence, and compounds that modulate telomerase activity are of significant interest in longevity and cell biology research.

Beyond telomere biology, Epithalon has been investigated in models examining pineal gland function and the regulation of melatonin secretion. Research has described its interaction with hypothalamic-pituitary regulatory axes, with studies noting downstream effects on cortisol and gonadotropin signalling in neuroendocrine models. These properties have contributed to its use as a reference compound in studies exploring the intersection of ageing, circadian regulation, and endocrine function.

Epithalon's small tetrapeptide structure confers relative metabolic stability compared to larger polypeptides, supporting its utility across a range of in vitro and in vivo experimental applications.

Stability and Handling

Epithalon is supplied in lyophilised (freeze-dried) form to preserve peptide integrity during storage and transport.

Standard laboratory handling considerations include:

• Refrigerated storage following reconstitution
• Protection from direct light exposure
• Avoiding repeated temperature fluctuations

Research Use Only

Epithalon is supplied strictly for laboratory research and educational purposes. It is not approved for therapeutic use and is not intended for human consumption.